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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a577786e3c5984cc97eb74b8d60960a8fafd0eb206dda232d3f9b0e2c4c534' 
  AND token = 'SB+9LRGZ28wTUEN1V/nlfmeQ7cDH/GwysaEA8y0DKio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}