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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df56d0e15f4e78c7b7882959a2a18725e7ee52f5d94d623122ff05b1e17c357d' 
  AND token = 'ivY9/10MN8rwhoY35QuVix+HNB+TZcUaXVipJUD2U7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}