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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6fc5609a5fdc3532455690feb6d91c2daf21a1dd6d3889e8defe493986c4eac' 
  AND token = 'jsYV/8TVlcXuQdiwttd1eoY4gKvc7h0ymUqQ9o2YPh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}