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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be15d0dfe8861f76fabad1587250f1be05c62c31dd15e1ee39d22a269ec4b023' 
  AND token = 'EnAM3WzytJimqBzmxeuPjMEL38TDjp4Pm7RFZQXnYTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}