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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '368eccf36b0814dea5ba1fb3d99bf817b4a5bac47ad619088b3616b127a3d114' 
  AND token = 'KjmAkurees4eV05T6HKujDjHv7JQUAhsfHsDN4VXjcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}