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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13222d526f96a80bdde6869627760b76d3a6e2b8f8bd9e2c7aa3d89c4584f27f' 
  AND token = 'x3I0IBYc2JEGr30ZZgRe/hZrgwYAkrIUb1QopW3G4KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}