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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6890201b5bed5a70bf30c32b19eb039b5b4e12af07b5182ca89989b2a8577441' 
  AND token = 'ZWaluycHDrk+UDojF0psYiv3gsXj86f2pHzpcQr7Ibk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}