SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd63dce3945ebc839e30f5de22d6dcbea77c1daac9ee3952d7126bfbf63772780' 
  AND token = 'XFxPEy5JSu1x9hhyHthBRdQxf5g2Da4udbZVzdWT2Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}