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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d50dda42153721bb71f4f4bc437abe266dd0fcc121fa9bb6b90987f6dc31397' 
  AND token = 'O8SB0ckv+YgxynT7T2I0MbWlsz3n+dNysFPA8vk+ODM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}