SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7ae01ffcd0c23b300571c8200bb205e2904786de5d8e974f42f5068303c396' 
  AND token = 'BtuvzS9sJ0xsx6V9y/FmkdIbA38fGVtWx+MDHFshmQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}