SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21605c6450ded46002daf1fb317ec97c4ae669b206b2c9510411301bb9ca2dd9' 
  AND token = 'HLVCa5cr1Uqi90qAtzGPX0mHpGO3Ljwr1EDPGyE/75E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}