SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a861b6b1f1180efda78c98e53ae95d639d01b218968e9e8f0e87a1662faac218' 
  AND token = 'sX7EzsWpOEXfTiP2eVlmdB/P1z9ZTq5WCvN85EXYNXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}