SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2473f9df9a7523f97ac488273b8c96643728b38f39d3251000fe985fb77a695' 
  AND token = 'UPL4keNHp1zUxIeR3VQr6RmkY50vLCLEp1LG3rNqwuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}