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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef69dfe4c4849c02a8262dc19f9fa0f2fb4161162d3fd551fdbbd75d51abf487' 
  AND token = 'MGSLHA49oM6d+WSpEv7t3AqjlpFWbg63SuNXbqEucgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}