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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b77aa12431a3d935489e91d0cfb92a3c68b68ea875c9db05e0ad1457fde58a' 
  AND token = 'AFiMpXn2lwdaAK0+epn5dchKcUIOhDqV4JnFkX6+kuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}