SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686538d200d167fad5ddcaa6ceae0842df740f35fbd4fb3845ea8afa2b94468e' 
  AND token = 'yj/H98QgbiOTNuqYVT+jExbB04P33zCSkEO02R+NrdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}