SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1131a5c1934dae376542f2d0f78bf1ce00edf304b489a6156f3e11e2e5a8e27' 
  AND token = 'nmEUVyg25xXnCGq0YLeGPs0MlVHsLGkJCjU7IDA4YyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}