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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5075a2a46abd21ad0aa459c54b1ab65d12ebda5becf7048bcdda273b9761bea4' 
  AND token = 'aADcM4IIA3aJbnupTVsbx8PWkbMgxJF0aHqHj/3nSPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}