SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344b682ca26b3bbe46b45b97c0a14cb2b532285ac2dbd88dfcddf4620118e2b6' 
  AND token = 'YD2UsBuoqaqQt0+GRZFRb3SGqBbNQMyG6Wi8X+cSdhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}