SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a222e7d033db465a4fdb6978f30a47631d6696cfcf768253fae96f018ff2ea9e' 
  AND token = 'L6A+bA+91yTBrYP8xdqIkLA2zckX77Lk+20haZ0URjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}