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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68cb43355b2b7db58f2a91e92e321e3a302d63aaf893b7f2135101facdba182b' 
  AND token = '0SjBfo40k7qdnot3KXVRoU8km3sj/pokgpvQ+72jiC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}