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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5578009ec235559c4771c64c123204f865a42e40e58f9c2c06c53dbc1f401499' 
  AND token = 'd4+6M55vVLB0TDLgtSVaj4uoQex+zS1DJ5anwlvQW7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}