SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '853d26345bfc92da6d8b1cc3d9acee5508a19883e69aa88740bda50110159f61' 
  AND token = 'lKLBlrjjWiO1sLhSRz0a/G0YQjNrOkYQ9js4slGKLDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}