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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12448663dfba08e26577a18d302fc68dac011d8bad4f04334be4938699f9cd5' 
  AND token = '9DBjJxdXjmhUA2/adqiRRAU5mSLk4XBOIC8Xe/4C83w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}