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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78526d64cb3b6dcf07acff3ce98a55cfe30b6e587f15e220ce88495e5ad47aaf' 
  AND token = '+WK/ni1okUpeXS42uocgI5+bOU6t39lPb9/XCHcZF8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}