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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88baee188297b09a1eb7cd5ee83378d8f91e43b4c23ae5324a4a5109f4cf64b7' 
  AND token = '3Df0M1pDAErf08935b0mJtIPjDN08ipYEN+IhATXwRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}