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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceca09f01fc5bb6f54941ffed39dc6682458ad398ad0d35ff0310b0024962f92' 
  AND token = 'skQ+pnnSJCzfLL2auSv0b8seujuMGxkIGKEmyUcUsBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}