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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43a7cfb8d7c8b3355989119d2fb1e905e44809cbae3750def9bb2eb09f27a04' 
  AND token = 'yR0cmMpPMa8cU5FQeiJXcolmfVeNLZiy1vZk2qkeEL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}