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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04830edc6d811e21b9df94d9d27111ca0f89e6453c70436db3508659e07c3b0' 
  AND token = 'LtjpPU54dZXLeiMqlgjniuXF2We+8aXwvmcgAZS8SaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}