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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08a0854a6b960dab4c38becfaa02e3d7adc1b8a089a54de5e63f759ffa8c85d4' 
  AND token = '4Ek3LjjLcqf26KcWJtDZQXYIHTG7LWOr2Qqhk1YY1tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}