SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3827dd3dccdd45c9dd16cdadc614964e56cf509c335717fc5b0ed53fe0a300' 
  AND token = 'YNcKtFC0KFMjbbMmz4S9M5o6nzK2uM6KaTgWiL1HU8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}