SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd14004bdc6f605e9a2b2f935c6d1cbbbdc81d66a907333cb84047000acca6964' 
  AND token = 'LjASL72MnGhVI5Uy46xWXdzRFCY31j1SzGp7RYRk7t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}