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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3cc7816ae98766b558ceddcc08f5d66b202237a2b32da365e2849fe8fe1449' 
  AND token = 'JxnaVy59sl1RxQYsduNvoYiTloJH8g79us0Ou4/Hu2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}