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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d48593491da718212616dc850009d7dcfc27c02f9a3f22118ff83fb88671bfb' 
  AND token = '3GpDytV4c7gJNqlSqUd2roLmPlrdFS+ThP/85rYNS+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}