SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848b07cd48ac88fbec36b6a5c74f73bd001323622b47b571d19d2a52eea526d9' 
  AND token = 'TUxmWUeWyk6Zqdv0nNv6wZHRtzRz6byYEqXkXXDqf3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}