SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52a6527d02f63a442c543460f03b83515cd1813cb852c0c2417f15bc89100d2' 
  AND token = 'W2kGuzEIOJCkNn68l3h0VH9n+0h4pM6ULMcYPB/9arU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}