SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bac92b6819bb5a837e9313072076df3c1c0605ae1abfee4d33527e80ac0c45f' 
  AND token = 'Xl5lfg18xVbg6nUMfdefm7VZM7DOxW5OXOjmqAMq6Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}