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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4efe2c7bea800141e8263dc78065856e6c29e2dd1442de318c4d507333a77d33' 
  AND token = 'kZeAvQfSLGpoZibHPaG2PZCFRlLCiYFL6OTBS18iLgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}