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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee57347995afc8e5edad33dc6da33b42f7a48972425b474fce526910d07fe71' 
  AND token = '1kUZl6mu/82VZKFhllu6iW/Cmr1ddHqfDi6RKidot4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}