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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fb6f289ca40cdad07e0c60cfd1ee50796bcc1e4d1e917d6b8d50786830934a' 
  AND token = 'OpJ9QVSPH3+ZW/xLq7F7NuIPPWgpwq4bMUwQN5FcDAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}