SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffbd5d1050c684ac3619f57e8022ebf2f4b4ec81ce092d2ab19df4be0abefe74' 
  AND token = '5sytw9r7poQYdZotOT+ARvSUtZLy40BmDu5uenYruOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}