SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d53d9b73d357bf8f3697b3c05aa90a4c850593e4c4a501061d4643807a99e56' 
  AND token = 'Um8Qv0n4GC2hCl3RtzWNmmfgsUjQSyNy4zRL5+tipqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}