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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64f8d9b6304a9a2434ae533dc1d27109e96c415d4ee728de258df98520778ee' 
  AND token = 'xjOnfJ4xVBCmQ0tOostmycF0YxONZJa+Dxmt9CyHovU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}