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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46571b8052d3d6a686c96c1da52eec0bc838bbd60f4817840465b8b98abfbf4' 
  AND token = 'fcR3dMny0O6vzkZTzQnNH1+LLB5ofFbGBhSQbB7j+4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}