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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c222d9e19e8d7a31a6d1d37600fd917364fabd6cf9ae19b8a6c9e0b1f470d94' 
  AND token = 'Hi8kV9YWEmMwHtfroT/E/E9l8LzcwML7QQXYC33rs/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}