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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e912f4e4c78a2bb488878980c8053f07916d070234c03287070a67dd5f116ba' 
  AND token = 'Xk5LrsejQn6Vh00vE8yHTml603e8oYO1yNQtXQLC9tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}