SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c84a73209d46593369b0e5152b3cea6bda780428a6856b9dd5e85b10a9b9c23' 
  AND token = 'HPUeIbUUVyFYD/Q7/nNHRix01cRA92SM+eQT/jMc2hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}