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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b4ffa3012b9181d9b76f78b5cef2911d7d142875d7e8c992aade447f358c16' 
  AND token = 'lXt8uZbJGmk6Swx5lUY4D0r07M0gbvcbbg8a2krKMEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}