SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b076bc86b3a6a5d4c80dec68df33d3640918742f2dbdb1b838c35fd6a4d291' 
  AND token = 'OTEy92KxEqdZiXwRLUmDntUZU0Toi6FNwQ3rkk8p8Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}