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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5292c300a4040357e6732b701ed163f32c28ced27d51d8cca0f5b33fcbe0ac79' 
  AND token = 'nZuzr7+1fMD3BCWFptu18bCa0rkXzSiiBQTvW7CyC1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}